Results
While clotting assays detect when blood clots, thromboelastometry (TEM) informs on how blood clots and if the clot gets and remains stable.
Typical reaction curves
Numerical data
| ROTEM® Parameter | Definition | Information |
Clotting time | time from start of measurement until the start of clot formation | initiation of clotting, thrombin formation, start of clot polymerisation |
Clot formation time | time from the begin of clot formation until an amplitude of 20 mm is reached | fibrin polymerisation, stabilisation of the clot with thrombocytes and F XIII |
Maximum clot firmness | clot stability and firmness | increasing stabilisation of the clot by the polymerised fibrin, thrombocytes as well as F XIII |
Maximum lysis | reduction of the clot firmness after MCF in relation to MCF | stability of the clot (ML < 15%) or fibrinolysis (ML > 15% within 1h) |
The different parameters in thromboelastometry (TEM) are dependent on:
- the activity of the plasmatic coagulation system
- platelet function
- fibrinolysis
- many factors which influence these interactions
- including several drugs.
This gives a complete view of the secondary haemostasis.